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November 27.2025

2 Minutes Read

Boost Brain Health: Exercise May Lower Dementia Risk by 45%

Middle-aged man exercising in a gym, potential link to lower dementia risk.

Exercise: A New Tool in the Fight Against Dementia

In a world where the pace of life continually ramps up, taking a moment to appreciate the value of physical activity could be one of the most transformative steps we can take for our health. Research shows that women and men alike in their midlife and senior years can reduce their dementia risk significantly—by up to 45%—through regular exercise. This finding comes from a recent study conducted by Boston University, which observed nearly 4,300 individuals over several decades.

The Power Years: Midlife Activity and Brain Health

The study identified two critical periods in life where increasing physical activity pays off significantly. For those between ages 45 and 64, exercise not only promotes overall health but is linked to a whopping 40% reduction in dementia risk. However, it’s essential to note that these benefits were primarily seen in individuals without the apolipoprotein E-4 (APOE4) gene, which is associated with a higher risk of Alzheimer’s.

Late Life Activities: A Silver Lining

Good news extends into later life as well; engaging in higher levels of physical activity for those aged 65 to 88 has proven associated with a 36% to 45% lower risk of dementia. This suggests that it’s never too late to start exercising. Notably, even those carrying the high-risk APOE4 gene can benefit—showing that physical activity late in life is beneficial regardless of genetic predispositions.

Why Does Exercise Matter?

So, what’s the reason behind this link between movement and brain health? Experts have several theories. Exercise boosts blood flow to the brain, reduces inflammation, and enhances neuroplasticity—the brain's ability to adapt and change over time. This neuroprotective effect may ultimately bolster cognitive health and stave off dementia’s onset.

Making Exercise a Priority

Incorporating daily physical activity into our routines can be daunting, particularly as we reach retirement. Yet, even small amounts of daily exercise can lead to substantial health benefits. With heart disease, diabetes, and strokes also influenced by a sedentary lifestyle, it becomes clear: staying active is essential.

As we ponder our health decisions, let’s remember that every step we take today towards a more active lifestyle contributes not just to our physical health, but also significantly impacts our cognitive well-being for the future.

Retirement & Exit Planning for Entrepreneurs

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Boost Brain Health: Exercise May Lower Dementia Risk by 45%

Exercise: A New Tool in the Fight Against Dementia

The Power Years: Midlife Activity and Brain Health

Late Life Activities: A Silver Lining

Why Does Exercise Matter?

Making Exercise a Priority

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